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News
Carbon Dots Emerge as a Powerful Weapon Against Superbugs and Biofilms
1+ day, 2+ hour ago (75+ words) A new comprehensive review published in the Journal of Nanoparticle Research surveys one of the most quietly promising corners of nanomedicine: carbon dots, nanoscale specks of carbon that are showing remarkable ability to kill bacteria and dismantle the sticky biofilms…...
Your Zip Code May Shape Your Breast Cancer Tumor’s Genetics and Your
1+ day, 2+ hour ago (617+ words) A landmark multi-institution study has revealed that the neighborhood a patient with metastatic breast cancer lives in may be written into the biology of the tumor itself....
Copper and Iron Cell Death Pathways Offer a New Two-Front Attack on Liver
1+ day, 4+ hour ago (55+ words) Hepatocellular carcinoma, the most common form of primary liver cancer, remains one of the world’s most lethal malignancies, and its treatment options have changed surprisingly little over the past two decades. Now, a review published in Medical Oncology argues that…...
Chemists Craft a One-Handed Molecule That Disarms a Cell-Death Protein
1+ day, 4+ hour ago (661+ words) A single protein called BAX sits at the gateway between life and death for human cells. When tissues are injured, stressed, or deprived of oxygen, BAX springs into action, punching holes in the outer membrane of mitochondria and triggering the…...
Shifting Identities: How Lung Cancer Cells Change Face to Outsmart
1+ day, 4+ hour ago (69+ words) Small-cell lung cancer has long been one of oncology’s most punishing adversaries. It grows with astonishing speed, spreads early, and presents a treatment paradox that has frustrated clinicians for decades: at diagnosis, tumors melt away under platinum-based chemotherapy, yet relapse…...
Children’s Aerobic Fitness Declines in Final Primary School Years,
1+ day, 5+ hour ago (611+ words) One of the most detailed long-term portraits of children’s aerobic fitness ever assembled suggests a troubling pattern in the final years of primary school. Researchers tracking hundreds of Norwegian children from first through sixth grade found that peak oxygen uptake,…...
Receptor Occupancy Fails to Predict Immune Activation in Pembrolizumab
1+ day, 5+ hour ago (55+ words) Pembrolizumab, one of the most widely prescribed cancer immunotherapies in the world, has long been dosed on the assumption that saturating the PD-1 receptor on T cells is the key to unlocking the immune system against tumours. A new translational…...
ApoA2 Drives Metastasis and Drug Resistance in Liver Cancer Through
1+ day, 5+ hour ago (541+ words) A protein long considered a quiet passenger in the bloodstream has been caught playing a far more sinister role in liver cancer....
AI Translates Light Microscopy Into Electron-Microscope Detail to Speed
1+ day, 5+ hour ago (534+ words) Mapping the wiring of the brain at nanometer resolution has long demanded a punishing trade-off: electron microscopy can reveal every synaptic cleft and organelle, but imaging even a cubic millimeter of neural tissue this way takes months or years of…...
New AI model maps the entire protein universe in a single view
1+ day, 5+ hour ago (464+ words) Every living cell depends on thousands of distinct protein families, each folding into precise three-dimensional shapes to carry out the molecular tasks that sustain life....